1999 Chevy Tahoe running rough

The engine on my Tahoe is running rough. It idles rough when first started but after it warms up it's fine. Occasionally, while driving it will skip badly. I have replaced the fuel filter. Before I spend any more $$ on guesses, is there any one thing I should be looking at?

Response:


First, check your Engine Codes. Then check your Compression as GM V series engines are known for dropping the last cylinder on the passenger side of the engine due to valve failure and sometimes No 1 cylinder. Also note that the V8 series has a problem with blown head gaskets on the passenger side.